AIDS-Kaposi Sarcoma and Classic Kaposi Sarcoma: are different ultrasound patterns related to different variants?

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AIDS-Kaposi Sarcoma and Classic Kaposi Sarcoma: are different ultrasound patterns related to different variants?

BACKGROUND Kaposi Sarcoma (KS) is a malignancy of endothelial skin cells with multifocal localization on the skin, lymph nodes and visceral organs. Although all clinical variants are associated with HHV-8 infection, specific differences in the clinical onset and in the natural history of AIDS-KS and Classic-KS have been described. The present randomised prospective-observational study aimed to ...

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Classic Kaposi sarcoma.

sented with a four-year history of asymp tomatic lesions on his legs. On examination, he had violaceous infiltrated areas on his feet and below his knees (Figure 1A; Appendix 1, available at www.cmaj.ca /lookup /suppl /doi:10.1503 /cmaj.101646/-/DC1). Histology confirmed a diagnosis of Kaposi sarcoma (Appendix 2, available at www.cmaj.ca /lookup /suppl/doi:10.1503/cmaj.101646/-/DC1), and immuno...

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Classic Kaposi sarcoma presenting as elephantiasis nostras verrucosa

Kaposi sarcoma is a malignant disease that originates fromthe lymphatic system. Different epidemiological, clinical andhistopathological variants of this neoplasm have been identified.Classic Kaposi sarcoma is one of the four main clinico-epidemiologicvariants. Cutaneous lesions vary from pink patches to darkviolet plaques, nodules or polyps, depending on clinical variantand stage. Kaposi sarco...

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Histological variants of cutaneous Kaposi sarcoma

This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and nu...

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Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma.

Interleukin-12 (IL-12) enhances Th1-type T-cell responses and exerts antiangiogenic effects. We initiated a phase 1 pilot study of IL-12 in 32 patients with acquired immunodeficiency syndrome (AIDS)-related Kaposi sarcoma (KS) whose KS was progressing while on antiretroviral therapy. Fifteen patients had poor prognosis T(1)S(1) disease. IL-12 was administered subcutaneously twice weekly at dose...

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ژورنال

عنوان ژورنال: Journal of Experimental & Clinical Cancer Research

سال: 2011

ISSN: 1756-9966

DOI: 10.1186/1756-9966-30-40